High-Throughput Experimentation (HTE) Software for Drug Discovery · University of Dundee

HTE is a field of chemistry that expanded exponentially in the past five years, and most pharmaceutical companies are currently using it in their workflows. This methodology allows multi-parameter optimisation of chemical reactions but also synthesis of multiple compounds (96 to 384) on a small-scale using plate chemistry.

Combined with the implementation of Direct-to-Biology (D2B) approaches, which involves the direct testing of non-purified mixtures, biological data is obtained faster. The combination of these methods greatly improves the Design, Make, Test, and Analyse (DMTA) cycle.